In S. pombe, an actomyosin ring that divides the cell during cytokinesis is assembled upon entry into mitosis and its maintenance and constriction depend on the septation initiation network (SIN), a signaling protein network whose components localize to the SPBs and the cell division site [11].
The C-spine is assembled upon nucleotide binding, while the R-spine is assembled upon phosphorylation of the activation loop.
The nine-fold symmetry of centrioles is in part provided by the cartwheel, one of the first centriole structures that is assembled upon their biogenesis and that displays that symmetry [ 4].
Inflammasomes are high-molecular weight, caspase-1-activating platforms that control maturation and secretion of IL-1β, which are assembled upon activation of intracellular receptors by various microbial and host-derived danger signals.
TCCs are assembled upon membranes, where they exert stimulatory effects on cell cycle and cell metabolism (sublytic TCCs) or promote cytolysis when present in higher amounts (lytic TCCs, also referred to as membrane-attack complexes [MACs]).
When it comes to Pakistan's strategic nuclear weapons, their parts are stored in different locations to be assembled only upon an order from the country's leader.
Office blocks and flats use components made off-site on an industrial scale, which can be assembled by crane, while houses are still made by methods going back to the Romans, brick upon brick, tile upon tile.
To confirm that the SCF complexes were assembled properly upon in vitro translation, we performed immmunoprecipitation with each F-box protein in the 35S-labeled in vitro translated samples (not shown) and tested whether the complexes containing β-TRCP were functional for polyubiquitination of β-catenin (Fig. S1 [E]).
Two finite elements for 2D analyses that imbricate each other while being assembled are designed based upon the triangulation of the domain.
Strings of amino acids are known as proteins, and once they are assembled, they fold up upon themselves (for chemical reasons), and their folded shape determines what other molecules, including other proteins, they will interact with basically, that they will stick to, one perhaps altering the other in the process.
