Strategies with a non-significant, a negative effect or did not meet the study objectives, compared with the primary objective of the authors, were classified as 'ineffective'mixedxeffectscts' was ascribed to studies that partially reached their objectives; and strategies with a significant, positive effect were classified as 'effective'effective
These differences in expression response can not be ascribed to mere study differences as the effect was reproducible in two studies carried out with different species, namely cynomolgus macaques (Macaca fascicularis) in the study by Kobasa et al. [10] and pigtailed macaques (Macaca nemestrina) in the Baskin et al. [8] study.
Some of these failures can be ascribed to poor study design, small sample sizes, or poor choice of primary outcome measures.
This can most likely be ascribed to the study design, as the data on bisphosphonate use were inaccurate.
This limitation cannot be ascribed to a study by Haug et al., 11 wherein employment was assessed before treatment, in addition to 3 and 12 months thereafter.
Differences in study results can be ascribed to differences in (a) study populations and study designs; (b) distribution of, or confounding by, other risk factors such as age, race/ethnicity, body mass index (BMI), and smoking; and (c) joints affected by OA and definitions used to define OA [ 3] and statistical methodology.
However, the differences between the white populations of Inter99, Whitehall II, and AusDiab were also significant and of the same magnitude, suggesting that part of the discrepancy in overlap can be ascribed to difference in study methodology such as the A1C assay method.
The lack of replication in our study could be ascribed to multiple differences between studies.
This may well be ascribed to the difficulty in studying this problem with an adequate experimental design.
We speculate that the apparent weaker interaction observed in the case-noncase analysis compared to the cohort analysis could be ascribed to the difference in study design.
