It can be argued that the elevated IOP placed a considerable physiological stress on a proportion of RGC somas as evidenced by their upregulation of the molecular chaperone Hsp27; yet, this response also occurred in rats with normal IOPs that underwent ON crush and may simply have been caused by damage to the axonal compartment.
While the costs associated with nonhuman primate studies is considerable, it can be argued that untold millions of dollars have already been spent supporting studies in probably inferior animal models, using irrelevant exposure paradigms given at the wrong life stages.
It could be argued that the political elite were previously able to exert considerable control over the narrative of events.
It is argued that our systematic approach offers considerable savings compared to the prevailing trial-and-error approach.
However it is argued that while these properties provide a considerable challenge at the level of identifying enzymes and metabolic interconversions ‐ indeed the definition of the plant metabolic network is still incomplete ‐ the real obstacle to predictive modelling lies in identifying the complete set of regulatory mechanisms that influence the function of the network.
For example in Sweden it is argued that the procurement entity has gained considerable autonomy within its political level, giving it a dominant position in planning the tender [7].
And just as it can be argued with, I believe, considerable validity that our present prob lems stem from an imbalance between our concern for the materialistic and nonmaterialis tic aspects of our life, from our obsession for the things of the flesh to the neglect of those of the spirit, so in the field of medicine is there a dangerous imbalance between the science and the art.
Undoubtedly, many NCD proponents would argue that considerable progress can be made with existing knowledge and strategies, even as the global health community struggles to understand and target the 'causes of the causes' (16, 54).
But, Deutrom argued, that cannot be proven.
However, it could be reasonably argued that empirical psychology has accumulated a considerable amount of empirical information about the distribution of reading skills scores in the population.
