Current professional guidance recognises that breach of proband confidence might be appropriate in narrowly defined circumstances where relatives are likely to suffer serious and preventable harm.
Although the error limits were adopted from Sinderby et al., these limits were arbitrarily chosen and may not be appropriate for defining synchrony, dyssynchrony, and asynchrony in mechanically ventilated children [16].
However, the authors did not acknowledge that the term RvD6 was appropriated in 2005 to define a specific variation between the M. bovis and H37Rv genomes [ 21].
Therefore, mortality is appropriate to define the end result of disease progression; however, it is not appropriate for describing disease progression in individual patients or in clinical practice.
These results implied that the focus of future KD research may involve B cells, C3, and the CD4/CD8 ratio, as well as the percentages of CD8+ T cells and NK cells; the absolute value of CD3+ cells may also be useful in defining appropriate diagnostic and laboratory tests for KD.
Moreover, it seems reasonable to think that risks for every municipality were similar in consecutive years, and so it would be appropriate to consider this fact in order to define the dependence structure in the data.
For example, the PPV and specificity of 'runny nose' or 'cough' in the absence of any other symptoms would be helpful in defining an appropriate list of symptoms.
If it proved possible to stratify patients into progressors and non-progressors on the basis of DNA methylation fingerprint at defined loci, such knowledge could be useful in defining an appropriate clinical trial cohort, for testing of anti-fibrotic drugs, for example.
Furthermore, the obtained data could be useful in defining the most appropriate timing of the follow-up, in specific cases and, if necessary, to develop better rehabilitation strategies in the event that the outcomes differ from the expected outcomes.
