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The costs of whole-genome sequencing have fallen so much that the technique can now be applied to populations for the first time, said Dr. Tishkoff, who paid the company Complete Genomics around $10,000 for each of the 15 genomes.
Simulations are an ideal method for evaluating the performance of alternative estimators because the methods can be applied to populations of known size.
However such studies have yet to be applied to populations in sub-Saharan Africa.
Predictive models should be applied to populations where they were validated [ 27, 28].
However, our method should not be applied to populations that are heavily structured over large geographic scales.
Thus, it is necessary to develop strategies to control this helminthic disease in areas of low endemicity, so that surveillance measures equal to those used in other areas may be applied to populations from these localities, leading to the eradication of schistosomiasis.
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Mean visit rates were computed for a number of age categories to be applied to population figures.
Many genomic approaches can be applied to population genetic studies of nonmodel species that lack a reference genome assembly.
Eventually these new tools may be applied to population studies to speed up data processing, enhance data accuracy, and reduce costs.
Moreover, the existing programs usually detect SNPs in a single individual, and cannot be applied to population samples where high-quality SNPs and allele frequencies require characterization.
These methodological quality recommendations should only be applied to population-based studies and address issues of coverage, bias, completeness and accuracy.
More suggestions(15)
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