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Moreover, these tools can be applied to polymorphisms identified by technologies other than sequencing, such as a SNP genotyping microarray.
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In addition, when applied to a genome-wide scan for candidate loci, the current methods must be applied to every polymorphism or core region that may exhibit strong LD with another.
To determine how readily B73/Mo17 Indel polymorphisms can be applied to fine-mapping with a W22 genetic background, we screened 201 markers for co-dominant polymorphisms in both the B73/W22 and Mo17/W22 inbred pairs (Table 1).
It can be applied to investigate genetic linkage and polymorphism in a population.
Especially SNPs, in several inbreed accessions can be applied to study the effects of these polymorphisms on other genome-wide features, such as phosphorylation sites.
If the genetic knowledge gained through comparative genomics using models is to be applied to crop legumes, the in silico polymorphism analysis must be effective for EST-SSR markers.
The wild type invertebrate neuroligins may therefore represent an interesting model that could be applied to the study of these autism-linked polymorphisms.
Increasing the number and diversity of domesticated genotypes sequenced may increase the discovery of polymorphisms that can be applied to Sl breeding populations.
The McDonald-Kreitman test (MKT), a robust test for positive selection using substitution and polymorphism data, could be applied to 715 alignments showing non-zero values in all four categories of nucleotide changes.
To explore if snapback single-strand conformation polymorphism (snapback SSCP) can be applied to the detection of known thalassemia point mutations.
As a next step, additional SNPs and other types of DNA markers such as amplified fragment length polymorphism (AFLP) markers could be applied to fill these gaps.
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