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Our analysis is not restricted to biomolecules, and can be applied to interactions within any polymer-like system of chains.
These properties can be applied to interactions such as intra-protein residue-pairs stabilizing the protein fold, inter-protein residue binding residues and protein nucleic acid interactions [25] [27].
The theory of professional closure, describing the carving out of exclusive professional definitions to create increased status or reward, can be applied to interactions between the various professionals involved in this intervention and their power dynamics (40).
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The MST and extended MST approaches were applied to interaction scores and complex predictions calculated from the combined results of the genome-scale TAP experiments of Gavin et al. (2006) and Krogan et al. (2006) in yeast.
Third, the classical interaction models can hardly be applied to study interactions (including pair-wise and high-order interactions) among the components of the biological systems and their complexity.
The same concept can be applied to predict interactions between proteins in different species.
In the following step a threshold can be applied to remove interactions with low weight (and therefore low likelihood).
The A-MDR method proposed herein can be applied to detect interactions among alleles, genotypes, and other categorical explanatory variables.
The extended definition of epistasis could be applied to the interactions among the chemicals and molecules in highly complex biochemical reactions [ 38].
Alternatively, eQTL-based analyses can be applied to candidate interactions between SNPs and gene targets identified through the experimental or computational approaches described above.
The test statistic, X, has a closed form, and thus can be applied to G × G interactions on a genome-wide scale.
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