Investigative journalists have done their best (the ARD reporter Hajo Seppelt just the latest in a heroic line), but until US law enforcement got involved – and now Interpol – there was little external influence that could be applied to effect change.
CA has an important limitation in that it cannot be applied to effect levels greater than the maximal effect achieved by the least efficacious compound included in the mixture (Silva et al. 2002).
The following discussion describes how this approach can be applied to effects-based and stressor-based assessments.
They can be applied to effects-based assessments to help explain observed conditions and they can be used in stressor-based assessments to make predictions.
This can be applied to genetic effects as well as permanent environmental effects.
Similar arguments can be applied to cohort effects, as well as to the presence of multiple change-points.
The same approach can be applied to study effects of the same drug under different dosages and time courses.
A similar approach can be applied to imaginative effect in a potato tatin, where new potatoes replace the apples, and are layered with a salty element or two such as feta, olives or anchovies.
A filter may then be applied to reduce noise effects and border effects.
Multilevel mixed effects regression models will be applied to test the effect of the intervention.
Then analysis will be applied to compare the effects of intervention between groups.
