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Therefore, the protocol can be applied for structure-based optimization of hit molecules.
Currently the same Kd value is applied for structures in hurricane and non-hurricane prone regions.
In order to widen the model scope, linear interaction energy was used as a tool for predicting activities of other genotypes based on the docked ligand poses while mutation binding energy was used to investigate the effect of each amino acid mutation in genotype 4. The model was applied for structure-based fragment hopping by screening a library designed by reaction enumeration.
The similar conception of hybridization can be applied for a structure which contains more than two layers of metals and dielectrics [6, 20].
The model can be applied for any structured material regardless of the origin of cementation.
Most of them could not be applied for welded structures serviced in the ultra-long life region so the new recommendations were discussed.
Tree alignments were introduced by Jiang et al. (1995) and can be applied for RNA secondary structure comparison (Le et al., 1989).
If the material under investigation is only available in the form of nanocrystalline powders or suffers from poor crystallinity, the methods of electron crystallography can be applied for determining the atomic structure.
By construction, sparsification can only be applied for calculating mfe-energy structures.
Remarkably, LCP method is not only propitious to GPCR, but also is able to be applied for none-GPCR protein structures determination (Suzuki et al., 2014).
In addition, self-organized effects can be applied for growing the nano-structures with controlled dimensions that are not only in the growth direction (thickness) but also laterally in the plane of the growth surface.
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