Sentence examples for be annotated to any from inspiring English sources
Afterwards, the standard bioinformatics analysis will annotate the clean tags into different categories and take those which cannot be annotated to any category to predict the novel miRNA.
Since the Corr-LDA model infers probability distributions from latent variables, moreover, miRNAs can be annotated to any functional modules, while mRNAs are restricted to the miRNA-inferred modules.
Gene products can be annotated to any number of GO terms within one or more of the ontologies to capture information about their various roles within these given domains.
As for other sequences that failed to be annotated to any one of the above databases, the ESTScan program (http://www.ch.embnet.org/software/ESTScan.html) was used to predict the 'CDS' (coding regions) and their orientations.
Here, k2 is the number of mRNAs included in GO terms, m2 is the number of mRNAs significantly co-regulated by miRNA pairs, n2 is the number of mRNAs that could not be annotated to any GO terms, and j2 is the number of mRNAs that are not significantly co-regulated by miRNA pairs and are also annotated to the GO terms.
For example, the human tyrosine-protein phosphatase SHP-2 protein has a single worm ortholog, ptp-2, which has not been annotated to any signaling pathway prior to our current study.
To restrict ourselves to the most novel predictions, we excluded any predictions in which the gene had previously been annotated to any GO term in the same branch as the predicted GO term.
An example of one such model is triglyceride module five from the MMC analysis that is also strongly correlated with weight and sugar and contains only three genes, of which only one is annotated to have any putative function (cytochrome P450).
Among the highly stress up-regulated (>8-fold) UniTags from chickpea nodules and roots (detailed in Table 3), five UniTags were annotated to ESTs with no homology to any characterized plant mRNA or genic DNA sequences.
The potential HGT candidates were then assigned KO numbers using KAAS, majority (>65%) of which were annotated to be the uncharacterized proteins without any assigned KO entries.
