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Based on the existing text annotations, all of these models could be annotated to a term in the extended vocabulary.
A cluster will be annotated to a GO term iff 50% of annotated proteins in that cluster share that GO term and all member proteins will inherit the annotation(s) of the cluster.
Every image in the database has to be annotated to a gold standard that the algorithms must meet.
Human Ortholog: If the probe set could not be annotated to a human ortholog, it was eliminated from further analysis.
Strikingly, metagenomic sample similarity increased from an average of only ∼1% when comparing all predicted proteins (Fig. 6A) to >90% when comparing only sequences that can be annotated to a SEED subsystem (Fig 9A).
As an alternative to such reference databases of gene expression signatures, genes could be annotated to a chemical response through text mining (TM) techniques.
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This left the set of mouse models that could not be annotated to an OMIM term.
When a macromolecular complex has been characterized, all subunits of the complex should be annotated to an appropriate complex term in the Cellular Component ontology (example, 'spliceosomal complex' [GO 005681] or 'nucleosome' [GO 0000786]).
Based on our annotation guidelines, clustered initiation sites are annotated to a single discrete location and closely spaced polyadenylation sites are annotated as a single 3′ terminus.
In order to handle variations in miRNA transcript lengths, a sequence read is annotated to a transcript locus from the annotation files when there is a minimal 50% overlap on genomics positions.
The quantitative evaluation of the MS analysis shown in Figs 4 and 5 was performed using the exponentially modified protein abundance index (emPAI 33, a label-free approach which allows the calculation of protein abundances on basis of the number of identified peptides that are annotated to a certain protein during the protein identification process.
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