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A protein encoded in the genome of a pathogen of interest can be analyzed for potential B-cell epitopes that could be targeted by the humoral host response.
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Flight data of a twin-jet transport aircraft in revenue flight are analyzed for potential safety problems.
First, the satellite data are analyzed for potential shock fronts.
Individual members of the P024C12 pool were analyzed for potential mutants.
For the identification of known plant regulatory promoter elements, 1 kbp upstream from transcription start sites of up-regulated genes were analyzed for potential consensus sequences using the 469 CREs experimentally validated in the literature (Mangeon et al. 2010; Tsutsui et al. 2011) and in the PLACE Database.
Each extracted sequence was analyzed for potential off-targets.
Novel SNP alleles were analyzed for potential differential splicing in vitro utilizing a splicing assay.
Hits ≥100 bp and ≥80% identity were analyzed for potential pathogens and commensal organisms.
Agrin mutants were analyzed for potential defects at the neuromuscular junction, by pharmacological treatments with aldicarb and levamisole, following previously described procedures [47], [71].
To identify the site of calpain action, human HDx-1 amino acid sequence was analyzed for potential calpain 1 and 2 cleavage sites using the web application SitePrediction [16].
Missense amino acid sequence variations were analyzed for potential pathogenicity using the PolyPhen (http://genetics.bwh.harvard.edu/pph/) [20] and SIFT (http://blocks.fhcrc.org/sift/SIFT.html) [21] sequence analysis algorithms.
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