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Because depletion of dopamine in the central nervous system (CNS) is known to be an underlying pathophysiological mechanism of depression (Hasler 2010), air pollution could affect depressive moods by inducing dopaminergic neurotoxicity, possibly due to oxidative stress (Block et al. 2004).
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CT-scanning and intracranial pressure-monitoring have proved to be valuable tools in the assessment of the diagnosis, but many patients still do not show satisfactory outcomes after CSF shunt surgery [ 20] suggesting an underlying pathophysiological process may not have been addressed by the procedure.
Although several studies reported serum uric acid as a marker of an underlying pathophysiological process, other studies hypothesis a potential causal link between serum uric acid and cardiovascular diseases.
There was an underlying deep physical attraction.
There is an underlying rumbling for change.
There's an underlying theme here".
"It's an underlying change.
But there is an underlying tension.
Migraine aura is the cortical phenomenon for which spreading depression is suggested to be the underlying pathophysiological process.
Although renal vascular disease was thought to be one of the underlying pathophysiological processes in LPHS early on [ 28– 30], more recent renal arteriography studies of patients with LPHS disagree with this hypothesis as the renal vasculature more commonly appears normal [ 4, 27, 31, 32].
If this is the case then almost nothing is known about the underlying pathophysiological processes responsible for this condition and at present there are no effective treatment options.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com