This view lends supports to the postulate that chronic prostatic inflammation is an inciting factor for BPH and PCa [1], [2] or that proliferative inflammatory atrophy is the precursor of PCa [3].
Although the mechanisms underlying an asthmatic episode are not fully understood, in general it is known that exposure to an inciting factor stimulates the release of chemicals from the immune system.
The role of MV as an inciting factor for lung fibrosis is poorly understood.
To test the role of climate as an inciting factor for SAD, a landscape-scale climate model was used to compare moisture status of declining and healthy aspen at the height of the warm drought in water year 2002.
Moreover, in the pathologic context of chronic immune complex-driven arthritis, where the inflammatory response is inappropriate and sustained, group V sPLA2 can counter-regulate disease activity via its capacity for promoting phagocytic removal of an inciting factor in disease.
In this respect, this article is an inciting call for action.
For some secondary RCVS cases, the use of cocaine or marijuana is the inciting factor responsible for the pathogenesis.
Interestingly, the smaller molecular weight IV iron compounds induced greater intracellular ROS generation, consistent with previous data regarding the appearance of non-transferrin-bound iron, which is the inciting factor driving the Fenton-Haber Weiss reaction [ 9, 10].
Several factors may either trigger or exacerbate this disease, and in line with previous studies [ 1, 2] obesity, diabetes and warfarin exposure were possible inciting factors or disease accelerators in our series.
This analysis suggested that there are predisposing and inciting factors at the large scale but the driving factors leading to individual infestations operate at smaller scales.
