Sentence examples for be an important upstream from inspiring English sources

Thus, we infer that Mil can be an important upstream regulator to the seven genes.

Specifically, mTOR appears to be an important upstream activator of HIF-1 α [ 15].

If this is the case, TPPP relocalization could be an important upstream target for developing treatments against MSA.

This later activity of the Gfi1-35 is not unsurprising considering Scl is thought to be an important upstream regulator of this element (Wilson et al., 2010b).

Together, these data suggest that Stat3 could be an important upstream regulator in the control of LGR4 expression in osteosarcoma cells.

Together, these data suggest that Stat3 could be an important upstream regulator in the control of PTPN13 expression in squamous lung carcinoma cells.

Therefore, it appears that RASSF1A is an important upstream regulator of Mst1 in the mammalian heart, but the overall impact of RASSF1A on the myocardium is a balance between cell-type-specific signaling and interactions.

Utilizing western blots, we found that propofol treatment reduced LPS-induced phosphorylation of IKKβ (Ser180) (0.31 with LPS only vs. 0.04 with LPS + propofol), which is an important upstream kinase for IκB degradation and subsequent NF-κB activation [21], [22].

The production of ROS is an important upstream event of NLRP3 activation (Tschopp and Schroder 2010).

NFAT is an important upstream regulator of COX-2 in metastatic melanoma.

NF-κB is an important upstream regulator of VEGF [ 27], a major angiogenic factor that induces endothelial cell proliferation.