Sentence examples for be an essential entry from inspiring English sources

Niemann-Pick C1 (NPC1), a highly conserved endo/lysosomal protein involved in cellular cholesterol trafficking, was recently identified to be an essential entry receptor for all known filoviruses (Côté et al., 2011; Carette et al., 2011; Miller et al., 2012; Ng et al., 2014).

Here we show, using transcriptomic profiling of susceptible versus non-susceptible cells in combination with genome-wide CRISPR Cas9 screening, that the major histocompatibility complex class II (MHC-II) human leukocyte antigen DR isotype (HLA-DR) is an essential entry determinant for bat influenza A viruses.

He argued that the port where the U.S.-purchased cranes are meant to go is not an essential entry point for Yemen's supplies, and suggested that attention instead be paid to alternative ports in Saudi-controlled parts of Yemen.

CCR5 is an essential component of the entry mechanism for HIV; if there is no entry, there is no infection and there is no risk of transmission to others.

An RNAi kinome (∼440 genes encoding protein kinases, phosphatases and regulatory factors) screen of VACV infection of Drosophila cells identified AMP-activated kinase as an essential entry factor that is conserved in mammals [6].

In further support of this, STRA8-positive cells were consistently detected in young adult mouse ovaries after HU-mediated blockade of premeiotic DNA replication, which is an essential step for meiotic entry in mammalian germ cells.

Viral entry is an essential target step for antiviral development, but FDA-approved HCV entry inhibitor remains exclusive.

HCV entry is an essential target step for antiviral development, but FDA-approved HCV entry inhibitor remains exclusive.

The prayer ritual is an essential component of Islam that requires entry into a state of physical purity (wudhu) through ablution, which is invalidated by voiding.

The NE-induced membrane depolarization is an essential requirement for opening VOCC, Ca2+ entry and smooth muscle contraction, and hence it represents an important mechanism of autonomic neurovascular control.

In this subcomplex, SufB acts as a scaffold, SufD is important for iron entry, and SufC is an essential ATPase.