DSB repair through HR process is an error free pathway, since it requires an extensive region of sequence homology between the damaged and template strands, whereas NHEJ is an error prone alternate pathway for the repair of DSBs, which essentially joins broken chromosomal ends independent of sequence homology.
Dilfer says he is more poised and confident now, even though Billick has made it clear that the premium he has put on his quarterback is to be an error-free, rather than a carefree, playmaker.
HR uses a homologous duplex to template repair of the break and is generally considered to be an error-free process; however, repair from a nonsister chromatid template can lead to loss of heterozygosity (LOH) or genome rearrangements (Symington 2002).
Aseltine and colleagues suggested that status measures may not be an error-free method of measuring change, because patients' standards, or the criteria they use to determine their ratings, may change following treatment as their frame of reference may change, so that apparently identical ratings are not, in fact, comparable.
The first is "organizing to execute," a command-and-control approach defined by strict project management and a clear plan for achieving the end goal, which is an error-free meal.
Neither supporters nor opponents of the death penalty are happy with this odd result.What Americans really want is an error-free death penalty, but this can never be guaranteed, as the recent spate of death-row exonerations has shown.
This group of 80 etchings by more than 40 artists from the collection of the Parrish Art Museum in Southampton, N.Y., is a special treat: each is an error-free master impression, pulled in the Lower Manhattan shop of Henry Voigt, who printed the works of many artists associated with the movement.
In contrast to NHEJ, there is an error-free DSBR pathway known as Homologous Recombination (HR) pathway where the cell employs a homologous DNA as template for the repair of the broken ends [17].
In contrast, HRR is an error-free repair mechanism which requires DNA homology.
Homologous recombination is an error-free repair pathway that requires a non-damaged sister chromatid to serve as a template for repair (Fig. 2).
