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Here we demonstrate that pharmacological blockade of p38MAPK may potentially be an efficacious intervention for the polyglutamine disorders.
Findings and Conclusions: 1. Developing an effective ITN distribution and re-treatment system ITNs have been shown to be an efficacious intervention against malaria.
Where there is an associated research program, it is either focused on evaluation [ 42, 43] or commissioned to explore the 'bottlenecks' that hinder what should otherwise be an efficacious intervention [ 44].
Therefore, the advantages and practicality of self-help treatments including computerised CBT (CCBT), i.e. self-help CBT using a programme on a website or on a computer without an online network, have been attractive, and it is believed that self-help CBT will be an efficacious intervention, especially for mild-to-moderate depression [ 15].
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Research indicates that exercise is an efficacious intervention for depression among adults; however, little is known regarding its efficacy for preventing postpartum depression.
Telephone-based counseling is an efficacious intervention strategy for maintaining leisure-time physical activity (LTPA) intentions and increasing LTPA behavior among adults with spinal cord injury (SCI).
The WHO and the Joint United Nations Programme on HIV/AIDS (UNAIDS) state that male circumcision is an efficacious intervention for HIV prevention, but should be carried out by well-trained medical professionals and under conditions of informed consent (parents' consent for their infant boys).
Although TKA is an efficacious intervention for treating pain, loss of function and diminished HRQoL, 10 to 30% of patients report poor outcomes or no improvement following the intervention [ 5- 8].
A number of randomised controlled trials have demonstrated that the Green Prescription is an efficacious intervention in relation to increasing physical activity and improving various aspects of health in previously low-active and sedentary adults [ 16- 19].
This study was motivated by recent findings of variability in health outcomes following TKA. 3 It should be emphasised that the intention of this study is not to assess whether knee replacement surgery is an efficacious intervention; it would be inappropriate to draw inferences about this from our study.
For example, while there may be insufficient evidence that Tai Chi in its own right is an efficacious intervention for depression based on the results reported by Yeung et al.[ 63], prior research has provided support for the positive effects of physical exercise [ 80], including Tai Chi [ 81], on mental health including depression.
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CEO of Professional Science Editing for Scientists @ prosciediting.com