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However, more recent data from mammals and Drosophila imply that, in vivo, RGS14 may instead be an effector of Ras.
It is localized in the mitochondrial membrane and facilitates the release of cytochrome C which is considered to be an effector of apoptosis.
The overlap between Rab26 and Rab33 prompted us to further investigate whether Atg16L1 may also be an effector of Rab26.
Importantly, Itln1 expression was itself shown to suppress prostate cell growth [ 37], and thus Itln1 appears to be an effector of prostate cancer repression.
T-cell-originated protein kinase may itself be an effector of BRAF, as phosphorylation of TOPK by RAF has previously been shown (Yuryev and Wennogle, 2003).
Given that ROS was found to be an effector of Zn2+-mediated cytotoxicity in ATP13A2−/− cells (Fig. 1), we exposed hONs cells to ZnCl2 to examine whether exogenous Zn2+ induced ROS production in hONs cells.
Similar(53)
RUN is an effector of the Ras-like GTPase signalling pathway associated with cell proliferation36.
Crepaldi T, Gautreau A, Comoglio PM, Louvard D, Arpin M. Ezrin is an effector of hepatocyte growth factor-mediated migration and morphogenesis in epithelial cells.
Both AP1, a Jun/Fos dimer transcription factor, and NFκB are known to be associated with Stat3 signasing16 as well as directly regulated by the TGFβ signaling pathway17, 18. ETS1 is an effector of the TGFβ signaling pathway19.
Czuwara-Ladykowska, J., Sementchenko, V. I., Watson, D. K. & Trojanowska, M. Ets1 is an effector of the transforming growth factor beta (TGF-beta) signaling pathway and an antagonist of the profibrotic effects of TGF-beta.
The lysosomal system is an effector of microbial degradation.
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