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This approach has gained popularity in several UK medical schools, and has been shown to be an effective vector for students' knowledge, confidence, and satisfaction [ 20].
Among the large number of cationic polymers described, chitosan is shown to be an effective vector because of condensing and delivered DNA, siRNA in vitro and in vivo [ 52, 53], and ODN in vitro [ 54].
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The key to the success of all these strategies is an effective vector that can direct appropriate expression of the therapeutic gene.
There is increasing evidence that ann-AUS may not have the intrinsic or extrinsic ability to be an effective JEV vector.
As stressed above, the endemic ann-AUS lineage may not be an effective JEV vector due to its local marsupial feeding preferences and relative inefficiency in transmitting the JEV genotype I strain and thus may provide northern Australia with a natural buffer zone [ 18].
This study shows that rAAV can be an effective and safe vector for gene delivery in liver transplantation.
Therefore, use of a whole genomic therapeutic gene to provide both replication and gene expression may be an effective gene therapy vector design, if the target cells are dividing.
With the extensive research on human immunodeficiency virus-1 due to the acquired immune deficiency syndrome pandemic, researchers have realized that this lentivirus, engineered to be devoid of any pathogenic elements, can be an effective gene transfer vector.
fluviatilis, in India, as mentioned above, could be an effective part of an integrated vector control plan.
Thus, to be an effective anti-cancer siRNA delivery vector, more studies should be performed, such as carrying siRNA against other oncogenes.
Minimizing oncogene activation by enhancers carried by therapeutic vectors should therefore be an effective method of lowering the risks of insertional mutagenesis associated with gene therapy.
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