In addition, inter- and intra-observer variations are an additional drawback of breast MRI [ 14].
Despite classical optimizations such as the Schnorr-Euchner (SE) enumeration [12], the SD originally presented in [11] offers by nature a sequential tree search phase, which is an additional drawback for implementation.
Lacking data on the degree of genetic admixture of the Swiss general population is an additional drawback.
Moreover, an additional drawback is their limited shelf life, which limits the viability of ready-to-use antibody-based sensors [ 2].
An additional drawback is a run-time complexity of O(n 3), which makes the method inefficient for working with datasets containing thousands of points.
An additional drawback is that basal insulin delivery rates were changed manually and automation, though technologically feasible, was not used.
Moreover, an additional drawback of snowball samples is that they sometimes require long chains, which are not easy to obtain.
An additional drawback is when an individual can acquire medication refills from multiple pharmacies outside the regular clinic.
The Pp-EBILWZ had an additional drawback, as its growth was slower than that of the Pp-EBIL strain it originated from.
Moreover, the fact that new compounds, like the presumably potent pitavastatin [ 37], are under several phases of research and development represents an additional drawback for performing the trials.
