The Louvre Palace was altered frequently throughout the Middle Ages.
These pathways are altered frequently in the high grade serous carcinoma.
As Table 2 shows, on average patients stated finding the information on their medication list frequently or always comprehensible (mean = 3.52) and receiving a new medication list after their medication was altered frequently or always (mean = 3.63).
To determine what are likely key nodes in pathways and functions, we hypothesize that, in addition to being altered frequently (by one mechanism or multiple mechanisms), these genes also exhibit multiple concerted disruption (MCD) in a given sample.
The observations that TUSC3 is altered frequently by multiple mechanisms at the DNA and RNA level and shows a strong association with patient survival, highlight the use of MCD in systematically identifying biologically, and potentially clinically, relevant genes.
The number of altered regions was similar in both types, although some regions were altered more frequently and/or with higher amplitude in IBCs.
Glycan-associated genes were altered more frequently than was predicted in two of the model systems, TGFβ-induced EMT and the cell line panels, but not in the cell migration model.
Using Cirrus OCT, average GCIPL was altered more frequently than average pRNFL in eyes of patients with RRMS (46% versus 33%, resp.; P < 0.001).
Environmental disturbance regimes are more frequently being altered by historically novel events and disturbance interactions, which may trigger reorganizations of new ecosystem states and processes.
Genes involved in oxidative stress response and squamous differentiation pathways were found to be frequently altered by mutation or copy number alteration or up-/down- regulation in squamous cell lung cancer [27].
