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If the 21-nt RNA that matches with the U6B snRNA fragment turns out to be from the mRNA for the β-actin-like protein, this RNA may be also a target of cytosolic Δ30 tRNase ZL.
We thought SHP1 could be also a target of γ-T3 in CSCs.
Because the sumoylation motif falls within the N-terminus that is shared between ZNF451 isoforms, ZNF451-L2a may be also a target of sumoylation.
Interestingly, it has been found that PLK1 expression is upregulated in the case of Retinoblastoma tumor suppressor (RB) inactivation, suggesting that PLK1 may be also a target of the RB pathway [ 12].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com