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Specifically, affinity enhancement can be tailored to the target-binding surface, typically the complementary determining region (CDR) loops in antibodies, whereas enhanced stability, expression or catalytic properties can be affected by selected changes to the core protein scaffold.
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Nevertheless, these results are interesting since they demonstrate the extent to which the accuracy and bias of genomic predictions can be affected by selecting the SNPs that are used to build the GRM.>>> However, selection of SNPs did not affect either the accuracy or the bias of genomic predictions when these predictions were made within-breed (Table 7).
Many of such problems are affected by selected excavation method.
Our reported prevalence of RVGE might have been affected by selecting only severe GE cases with more severe disease characteristics, including longer hospital stays.
Secondly, according to the estimation method of social network sizes by random sampling presented in (Katzir et al. 2011), we argue that the quality of data sets cannot be affected by random selected nodes.
The results of these studies may be affected by the keywords selected from the relevant documents – but, despite its importance, the existing literature has seldom explored strategies for selecting and processing keywords from patent documents.
Nucleotides in third or wobble codon position may not be subject to positive selection but, their frequency in a given population could be affected by proximity to selected regions through genetic hitchhiking [ 29, 30].
4, we present our results in a design-oriented format that reveals the way in which stability would be affected by variation of selected parameters, and hence facilitates the choice of parameters for stable operation [20].
Supplementary Data 2 lists the 69 different transcription factors whose DNA binding affinity was predicted to be affected by the 251 selected HGMD regulatory SNPs/mutations from the 13 different disease states under study.
For more details about what will be affected by the restore, select a point from the list and click the "Scan for affected programs" button.
Di-nucleotide content may be selected for its effect on mRNA structure but it may also be affected by mutation bias, or selected for some other reason, for example for nucleosome positioning [ 56- 58] or transcription pause sites [ 59]. (ii) Frequency of polypurine tracts is increased in exons and may affect thermodynamic structure.
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