Sentence examples for be affected by binding from inspiring English sources

In particular, the stability of different types of looped DNA-lac repressor conformations has been shown to be affected by binding of the catabolite activator protein [36], [37].

This may affect the cytotoxicity of SBL because cell susceptibility to RNase can be affected by binding as well as the internalization or translocation of RNases as described above.

Clearly, gal-1 residues at the quintessential lactose-binding site are affected by binding to GRG.

The activity of neither protein was affected by binding to dystroglycan, nor was dystroglycan a substrate, but surprisingly the localisation of dystroglycan with MEK or active ERK was quite different within the cell [ 45].

The C-terminal regions in PDK1 (peptides Ile Ser and Ile Asp) and corresponding C-terminal regions in PDK2 (peptide Leu Asp) were affected by binding to the E2·E3BP core.

However, in order to interpret the dynamics and interaction experiments, it is necessary to first obtain a resonance assignment so that the observed spectral peaks may be matched to atoms in the protein (e.g. to localize which atoms are affected by binding).

This is further supported by the presence of Trp237 in the 2-OG binding pocket, which would be affected by ligand binding.

For very potent, high-affinity compounds this assumption may not be valid, and under such conditions the concentration of unbound drug will be affected by its binding to the pharmacological target and the binding model becomes 3: is.2where L0 is the initial, total drug concentration.

Because the previous analysis of HSF binding events on polytene chromosomes was not of sufficient resolution to determine which genes HSF associated with at heat shock temperatures on a global scale, we set out to determine what genes may be affected by HSF binding by identifying the genes closest to each HSF binding site.

In many cases a protein may bind cooperatively, and it may be affected by further binding proteins.

The activity and expression of Humanin can be affected by the binding of other proteins to Humanin; for example, insulin-like growth factor-binding protein-3 functionally interacts with Humanin, tripartite motif-containing protein 11 destabilizes Humanin protein, and V-set and transmembrane domain containing 2 like protein (VSTM2L) inhibits Humanin activity.