Sentence examples for be administered less frequently from inspiring English sources

Much effort is thus focused on developing dosage forms that can be administered less frequently.

Darbepoetin alfa, a recently approved erythropoietic agent, can be administered less frequently than Epoetin alfa due to its approximately 3-fold longer half-life.

In this setting, darbepoetin alfa has a three-fold longer terminal half-life than rHuEPO (25.3 h vs 8.5 h) and can be administered less frequently with the same efficacy as rHuEPO.

Although conventional amphotericin B is the least expensive antifungal drug and is recommended for empirical antifungal treatment of IPA, this drug could be administered less frequently than other antifungal drugs due to side effects or contraindications.

All commercial bisphosphonates have been used to treat bone metastases, but zoledronic acid (ZA) is currently the preferred option due to its great potency and its ability to be administered less frequently (Polascik and Mouraviev, 2008).

There is also a controlled trial that has shown ertapenem to be as effective in the treatment of diabetic foot infections as piperacillin/tazobactam (one of the most commonly used agents in our study), and a comparative study of costs estimated ertapenem to be less expensive, primarily because it had to be administered less frequently [ 32, 33].

In male breast cancer adjuvant treatment was administered less frequently.

Donepezil was administered less frequently in men than in women (35.14% versus 43.06%; P<0.001).

It is noteworthy that both CAT item usage and absolute item difficulty were significant predictors in the multivariate models given that these variables are strongly and negatively correlated (r=−.67), indicating that items of high and low difficulty are administered less frequently by CAT.

For items with DIF, those items administered most often by CAT were more likely to be detected than items administered less frequently.

Daily vitamin D administration is at least as effective at elevating serum 25-OHD levels as compared with higher doses of vitamin D administered less frequently.