Wasson speculated the poison used to kill Claudius was derived from death caps, with a fatal dose of an unknown poison (possibly a variety of nightshade) being administered later during his illness.
In a final set of experiments, we investigated whether IdeS is effective also when the enzyme is administered later during the time course of the thrombocytopenia.
Other antibiotics including azithromycin and ceftriaxones were administered later due to persistent fever.
In all patients, the FFP was administered later than 30 minutes (TP2) after the start of the MARS treatment.
Moreover, in the observational study, amiodarone was administered later than lidocaine, and it was not administered with the recommended doses to all the patients.
For example, available preclinical data of experimental stroke suggest that EPO is much less effective if it is administered later than 6 hours after the insult [ 37].
Notably, in protocol 3A and 3B, atipamezole was administered after 10 minutes of immobilisation, thus in this study we can not report on the duration of immobilisation in these 2 protocols when atipamezole was administered later or not at all.
Furthermore, the sooner a patient is seen and managed by rheumatologists results in superior clinical responses and increases the chance of disease remission 10 14 than if the same care is administered later in the disease course.
The participating centers were allowed to freely select from the three available antithrombin concentrates used in our country (CSL Behring, Japan Blood Products Organization, Nihon Pharmaceuticals Co., Ltd .. Three days later, antithrombin was administered after the taking of a blood sample for evaluation in the morning.
The first dose of their assigned medication was administered after transfusion of a further 2 units of RBCs (8 units in total), and a second and third dose were administered 1 and 3 hours later.
