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We suggest that edaravone and possibly other radical scavengers or antioxidants should be administered in response to ROS generation, meaning that the bedside monitoring of ROS could shed more light on the potential benefit of these agents.
Most guidelines recommend that cryoprecipitate be administered in response to fibrinogen levels decreasing below a certain threshold; however, in an emergency setting, turnaround times for the Clauss fibrinogen assay are too long to effectively guide administration of haemostatic therapy in patients with acquired coagulopathic bleeding.
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Dr. Arthur said it was "absolutely irresponsible" to suggest that the 5-year-old horse "had those drugs in it before it was filmed," and that they were administered "in response to the injury".
This output signal represents a diagnosis, which either can be measured using FRET techniques, cascaded as the input of another logical deduction with different rules, or even be a drug that is administered in response to a set of symptoms.
Strategic sea lice treatments form part of the integrated health management programme adopted by Scottish salmon producers and not all treatment episodes are administered in response to a substantial sea lice challenge.
Because SSI typically is administered in response to a glucose value above a predetermined threshold, patients given SSI are hyperglycemic by design.
A report from the UK estimated that 95% of cryoprecipitate given during cardiac surgery was administered in response to haemorrhage and not given prophylactically.
A potential bias in treatment might exist once the diagnosis is known, as type C fractures are considered a more severe injury, and the patient receives more fluids than the fluids being administered in response to resuscitation.
If systemic treatment would be administered in a neoadjuvant fashion, response to this treatment might be used as a selection criterion for further invasive procedures: local responders not developing metastases may be better candidates for extended surgery, whereas those who show local progression or even develop metastases under chemotherapy could be spared unnecessary extended surgery.
Following the cycle of chemotherapy, an additional course of ssHHT could be administered in case of response at the discretion of the treating physician, or any other additional chemotherapy.
Additional cycles, up to a maximum of 10, could be administered in patients exhibiting a complete response (CR) or partial response (PR).
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