Medium molecular weight HES 130 with a low degree of substitution (0.4) was well tolerated and can be administered in larger doses over longer periods of time without relevant effects on hemostaseology compared to a crystalloid group.
Finally, the questionnaire was administered in large quantities.
HES is suspended in saline, and when it is administered in large volumes intravenously – as in the case of hemodilution – this could lead to a nonphysiologic chloride load and metabolic acidosis, as suggested by the observed disturbance in acid-base balance.
CASP items have been administered in large population-based samples such as the English Longitudinal Study of Ageing (ELSA) waves 1 5 (Marmot, Banks, Blundell, Lessof, & Nazroo, 2003), the 2004 U.S. Health and Retirement Study (Clarke, Fisher, House, Smith, & Weir, 2007); and the British Household Panel Study (BHPS) (Taylor, Brice, Buck, & Prentice-Lane, 2001).
Vassallo said that fentanyl would need to be administered in a large, ongoing dose in order to kill the inmate, a departure from past lethal injection protocols.
10 As mesenchymal stem cells need to be administered in relatively large numbers, obtaining sufficient cells of good quality is challenging.
In contrast, fibrinogen concentrate is reconstituted as a smaller volume, which allows large doses to be administered in a few minutes.
The volume of the KX injection was too large (1.25 mlkg−1) to be administered in one hind leg, therefore, it was divided in half and injected intramuscularly in the caudal parts of the femoral musculature of both hind legs.
The well-known stop-signal reaction time task, which measures the ability to stop an ongoing response, was administered in a large sample of close to 1,900 14-year old adolescents while lying in the MRI scanner.
