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Although anti-HMGB1 monoclonal antibody might be administered in cases of severe infection in general clinical settings, CRRT requires intensive care, resulting in higher medical costs.
Although the cost-effective treatment of CDI may necessitate the appropriate use of the less-expensive metronidazole, vancomycin should be administered in cases expected to become severe or life-threatening.
These guidelines recommend 1x 250 mg ceftriaxone i.m. or 400 mg ofloxacin per os as first choice treatment, or 400 mg cefixime per os or 500 mg ciprofloxacin per os can be administered in cases of uncomplicated gonorrhoeal urethritis or cervicitis.
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Iron supplementation will be administered in case of anemia for children not requiring nutritional supplements (otherwise, iron is already included in nutritional supplements).
Included on the form was the dosage of intramuscular epinephrine, intravenous hydrocortisone and oral antihistamine to be administered in case of a severe allergic reaction.
Antimalarial rescue treatment will be administered in case of treatment failure, repeated vomiting or malaria infection with species other than P. falciparum.
Topical antibiotics may be administered in case of severe infection, with additional topical steroids or steroid-antibiotic combination preparations if necessary [ 4– 6].
Successful therapy with L-AmB has also been reported in case reports [ 77, 161] and might be administered in case of contraindication, intolerance, or poor response to voriconazole (BIII).
Following the cycle of chemotherapy, an additional course of ssHHT could be administered in case of response at the discretion of the treating physician, or any other additional chemotherapy.
Pharmacological targeting of β-adrenergic receptors is a well documented first-line therapeutic approach for the management of cardiac arrhythmias, cardio-protection after myocardial infarction, and hypertension [1], [2], while β-agonists are administered in cases of bradycardia, heart block or asthma [3], [4].
Systemic steroids were administered in cases of severe hypoxemia with interstitial pneumonia cases (n = 1).
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