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A specific activity of 1−50 Ci/mmol at the time of injection proved to be adequate for imaging F-labeled 3 in a 20 min PET scan 1 h after injection.
The resulting radiolabeled nanoparticle was stable in blood for more than 24 h, and therefore this chelation approach was considered to be adequate for imaging the pharmacokinetics of the lower molecular weight dendrimer (7 8 kDa) which is expected to have a short blood half-life.
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While the majority of patients demonstrated evidence of tumor targeting, one patient (no. 8) was negative in spite of tumor size that was adequate for imaging with relatively low IHC and several had relatively low tumor accumulation compared to the normal liver background.
This resolution proved the imaging performance to be adequate for obtaining individual cell imaging.
Such a frame rate was shown to be adequate for in vivo imaging of Fluorescein stained human bladders using a confocal laser endoscope [ 28].
The vesicular acetylcholine transporter (VAChT) represents an appropriate target to establish PET radiotracer that are adequate for brain imaging the loss of cholinergic terminals.
While these systems have proven to be adequate for multiphoton and pump-probe microscopic imaging applications, the temporal separation of the laser pulse train (around 12.5 ns) is long compared to the fluorescence lifetimes of many common fluorescence species.
Using 67Ga as a γ-emitter might be adequate for single-photon emission computed tomography (SPECT) imaging; however, since it is currently not available in sufficiently high purity, it cannot be used to label our peptides with high-enough specific activity for in vivo experiments.
Lumpectomy may be adequate for AME only.
The breath-hold technique is required for CTp imaging of the chest and upper abdomen to avoid respiratory motion; free breathing is adequate for CTp imaging of the head, neck and pelvis.
The low-affinity variant GAP3 is adequate for ratiometric imaging in the endoplasmic reticulum and Golgi apparatus, and it can be combined with conventional synthetic indicators for simultaneous measurements of cytosolic Ca2 +.
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