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Any environmental change that is experienced abruptly by a species, and in which adaptation by natural selection is required for it to persist, can in principle be addressed with models along the lines of those we have explored here.
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This study has demonstrated that fetal mesenchymal stem cells are a valid and viable model for studying aspects of adipogenesis that can not be addressed with traditional models.
This hypothesis needs to be addressed with animal models in future studies.
Data gaps can sometimes be addressed with computer models as well as knowledge of chemical analogs and structure activity relationships (which predict how chemicals will act based on their structure).
Additional extrapolation to environmentally relevant doses can be addressed with PBPK modeling.
Quality and safety issues such as crust development, oil pickup and acrylamide formation can be addressed with such a model.
These issues, which are sometimes very important, can be addressed with the probability-model approach statisticians favor.
The activities at additional ion channels are often cited as a means of improving specificity; it may, however, be more important to consider the multiple influences on exposure, which could now feasibly be addressed with a PBPK modeling technique.
It is going to have to be addressed with a health-care model.
This discordance between SC SPECT uptake measures and CTP score for certain patients may be addressed with improved liver function classification models.
This could be addressed with the use of multivariate models if the relevant traits could be identified.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com