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All of the system design aspects can be addressed using validated parametric library components.
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Clinically relevant outcomes, such as fibroid-related symptoms, quality of life, should be addressed and measured using validated instruments, such as a pictorial blood-loss assessment chart, Short-Form McGill Pain Questionnaire or visual-analogue scale for pain, and the uterine fibroid symptoms quality of life (UFS-QOL) questionnaire.
However, our study shows that there are data quality issues and key data gaps that need to be addressed before the model can be further refined, validated and then used for decision making.
Information will be collected using validated questionnaires.
Quality of life will be assessed using validated questionnaires.
Adverse effects will be assessed using validated questionnaires.
Personality traits can be evaluated easily, using validated questionnaires.
Data analysis should ideally be performed centrally, using validated software.
Wedelolactone content was determined using validated HPLC methodology.
Ethnicity was determined using validated surname algorithms.
Assessments were done using validated test methods.
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