In recent years, this limitation has been addressed by development of portable or unilateral NMR [22 24].
This issue was addressed by development of a bacterial carrier for targeted delivery of lycopene.
The need for adequate characterization of unbound cefazolin PK was addressed by development of an empirical population PK model for both free and total cefazolin during pregnancy.
Although the former will depend on the marketplace, the latter is already being addressed by development of novel analysis tools (7, 9, 11, 28 ), global databases (10 ), and access to shared server systems and parallel computing networks (29, 30 ).
This issue was addressed by developing Low Impact Development (LID) practices to deliver better hydrologic function and improve the environmental, economic, social and cultural outcomes.
This limitation may be addressed by the development and use of appropriate biomarkers.
These studies cite a range of complications that could be addressed by the development of appropriate guidelines.
The desire to contribute to the family income as expressed by participants in this study could be addressed by the development of socioeconomic interventions as, for instance, done by Ebenso et al. [ 28].
The poor prognostic value associated with RRP is important and may be addressed by the development of prediction matrices to quantify the risk of RRP at one year in terms of baseline data.
The lack of conceptual and methodological clarity in preference research can be addressed by the development of a conceptual map on preferences, incorporating all contributions from all relevant disciplines and a taxonomy to systematically categorise the different types of research (and measurement techniques), as suggested by Brooker et al. [ 13] and Chong et al. [ 3].
These limitations are starting to be addressed by the development of personalized treatment selection techniques; these combine patient characteristics from clinical trial data to form a risk score and then performing analyses on subgroups using a two-stage process that allows for treatment responses at an individual level to be made [ 16, 94, 102].
