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This method could be adapted to sequence the V3 or V5 region suitable for uncovering the intestinal microbiota [5].
Sequencing-by-synthesis technologies generate data by repetitive sequencing, or oversampling, of a given DNA segment and can be adapted to sequence one particular DNA region at great depth [1] [3].
Moreover, this multiplex method can also be adapted to sequence other genes.
Emerging techniques for high-throughput single-cell analysis (allowing for heavy and light chain pairing) will soon be adapted to sequence multiple genes along with the BCR, and eventually the full genome.
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A whole-genome shotgun strategy was adapted to sequence the genome of Cp0710 using both Roche and Illumina technologies.
Our methodology can also be adapted to protein sequence alignment.
It can be used as part of the reproducible, automated next generation sequencing pipeline Omics Pipe [ 16], as a standalone reporting tool or it can be adapted to existing sequencing pipelines.
However, this approach can be adapted to other sequencing methods that detect specific SNPs and allow for quantitative determinations at SNP positions.
Given that the Martin-Löf approach is a generalisation of von Mises', it is not surprising that it too can be adapted to permit biased sequences to be random.
The method can be adapted to any available sequencing system.
Although it can be adapted to analyze DNA sequencing data, a previous study shows that the underlying statistical models used by ABSOLUTE do not comprehensively describe the characteristics of DNA sequencing data and therefore may sometimes gravely misestimate the tumor impurity and ploidy (Oesper et al., 2013).
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