Counting for each metabolic reaction and transport process in how many stage-specific flux distributions it is predicted to be active when using the improved algorithm (see Additional file 13), reveals that nearly 350 reactions carry a non-zero flux in all 96 flux profiles that are derived from gene expression samples extracted during the IDC.
For simplicity, in this paper, we assume that there are no interference signals from the transmitting antenna of relay R 1/R 2 to the receiving antenna of relay R 2/R 1 since only one relay is active when using DSSC technique, so we do not need to consider the link between two relays [18 20, 22].
For example, anti-EGFR antibodies in wild type KRAS patients may only be active when infusional 5-FU regimens are used, but not when capecitabine based protocols are applied [ 4].
They light up and are active when being used, but lay dormant otherwise.
In the phase II studies, cisplatin treatment was found active when used at a dose of 70 mg m−2 in six courses during 7 weeks (i.e. week 1,2,3 and 5,6,7) in combination with VP16 in advanced cervical cancer, pleural mesothelioma, melanoma and NSCLC (Planting et al, 1997, 1999).
These results demonstrate that enzastaurin, by targeting critical proteins such as pAkt and VEGF pathways, is not only active when used alone, but also can abrogate the resistance to EGFR inhibitors, strictly depending on those proteins.
The ability of TgCDPK1 to utilize KTPγS depended on the presence of a glycine gatekeeper (CDPK1G) since the mutant kinase (CDPK1M) was unable to thiophosphorylate dMBP, despite the fact that this mutant enzyme is fully active when using ATP.
And the image features after convolution become less sparse (i.e., have higher probability of being active) when whitening pre-processing is used.
Ryan danced around questions about why Tebow was active when there seemed no plan to use him.
Around 90% of the data points are active when a threshold of 10 μM is used, while a roughly equal partition (55/45%) occurs at a threshold of 6.5 log units (Additional file 1: Figure S3).
