Sentence examples for be active in human from inspiring English sources
We further investigate the role of IL-1 in incisional wound biology and its effect on wound chemokine production in vivo and whether this mechanism could be active in human subjects.A well-characterized murine model of incisional wounding was used to assess the in vivo role of IL-1 in wound biology.
ZFRs with catalytic domains from Tn3 resolvase and Gin invertase have been demonstrated to be active in human cell lines [15], [16], illustrating the potential applicability of these enzymes in mammals and other eukaryotic organisms.
These enhancers may also occur inside genes, but how many may be active in human cells and their effects on the regulation of the host gene remains unclear.
This evolved PM1 laccase was recently tailored to be active in human blood (at pH 7.4 and high NaCl concentration −150 mM-) [ 31].
High expression of a number of CYP enzymes in CTNNB1-mutated human hepatoblastoma samples indicates that comparable mechanisms of β-catenin-dependent CYP expression might be active in human and rodent liver cells (Schmidt et al. 2011).
In two previous reports, we described the directed evolution of a HRPL from basidiomycete PM1 strain CECT 2971: i) to be expressed in an active, soluble and stable form in Saccharomyces cerevisiae, and ii) to be active in human blood.
The scientists wondered whether a protein similar to the honeybees' royalactin may be active in humans.
Researchers in her lab also plan to use the worms to screen a library of chemicals known to be active in humans to assess their effects on age-related declines in cognitive function in worms.
Therefore, molecules that pass the Lipinski rule are expected to be active in humans after oral admission.
Some such agents are known to be active in humans and are used successfully in the treatment of a range of human hormonal conditions".
Of the various candidates that have been shown to oxidize benzene in mammalian in vitro systems, only CYP2E1, CYP2B1, and CYP2F1 appear to be active in humans, and these have apparent K m values in the order 2F1 < < 2E1 < 2B1 (Koop et al. 1989; Nedelcheva et al. 1999; Powley and Carlson 2000).
