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Another example of catalyst that has been widely reported to be active at low temperature is a catalyst based on sulfated zirconia [8, 9, 10, 11, 12, 13].
Since halophilic enzymes are adapted to function at high salt concentrations, they are also found to be active at low water availability.
Additionally, the enzyme is predicted to have higher flexibility compared to mesophilic or thermophilic enzymes, allowing psychrophilic enzymes to be active at low energy costs [ 7].
The intraarticular availability of adequate levels of IL-1ra is important, as IL-1β is considered to be active at low concentrations and relatively high levels of IL-1ra are required to inhibit the effects of IL-1β [ 29].
Although several i-type lysozymes have been shown to be active at low temperatures, the enzyme is stabile even after prolonged heating or long-term storage at room temperature [ 51].
In our experiment, UL41 transcripts appear to be differentially expressed only at 8 h pi suggesting that the vhs activity can be attributed to the newly synthesized proteins and not to the vhs proteins present in the virion tegument at the moment of infection and that the vhs protein should be active at low level.
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The lower value for MIC represents more potent antibacterial activity (strong bacterial inhibitors are active at low concentrations).
A lower MIC value indicates stronger antibacterial activity, as strong bacterial inhibitors are active at low concentrations.
We have indeed developed novel multidentate small molecule inhibitors of VHR that inhibit its enzymatic activity at nanomolar concentrations in vitro, and are active at low micromolar concentrations on several cell lines and primary cells.
Wild-type KlenTaq1 is active at low and high temperatures, with a 74°/37° activity ratio between 2.5 and 4.
Therefore, it becomes imperative to design new catalysts that are active at low operating temperatures.
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