We reasoned that if the transformed neurons did made functional connections within the antennal lobe they would be postsynaptic to the olfactory sensory neurons and would be activated upon the activation of the antennal nerve.
As further fundamental pathways, the MAPK/ERK and PI3K/AKT signalling axis have been reported to be activated upon PKC activation, which leads to cell proliferation and anti-apoptosis (Balendran et al, 2000; Goekjian and Jirousek, 2001).
Currently, three different pathways are believed to be activated upon Wnt receptor activation: (1) the best understood canonical β-catenin cascade, (2) the non-canonical planar cell polarity (PCP) pathway, and (3) the Wnt/Ca2+ pathway.
We show that the IGF-1R is expressed in most AML cell lines and can be activated upon stimulation with IGF-1; however, no constitutive activation of IGF-1R activity is seen in AML cell lines.
Earlier results showed that PKCα can be activated upon thrombin treatment and can enhance RhoA activity in endothelial cells, therefore mediating cell contraction [ 40, 41].
The downstream activation of the pro-apoptotic ASK1/JNK cascade, known to be activated upon severe ER stress, as well as our findings that expression of DN IRE1 α and inhibition of JNK both markedly suppressed the apoptotic effect of CBD, provided evidence that CBD causes ASK1/JNK-induced apoptosis in activated HSCs through an ER stress-mediated mechanism.
Conceptual change, in this perspective, involves altering the structured priorities of knowledge elements - i.e., altering the likelihood that particular pieces of knowledge will be activated upon recognition of specific contextual cues.
Due to the extended N-atom region, multiple spin-switching events can be activated upon application of an external magnetic field and as a function of the electron filling.
When 5- to 6-year-old children actively manipulated an object while hearing a new label and then heard the label again, motor areas of their brains were more likely to be activated upon subsequent viewing compared with when they were only allowed to passively watch an experimenter manipulate the named object (James & Swain, 2011).
Although the Dominion takes heavy losses to the Zerg, the Raiders defend the artifact from Kerrigan until it can be activated; upon detonating, it destroys all nearby Zerg and leaves Kerrigan human again.
These genes may therefore be ready to be activated upon differentiation.
