Sentence examples for be activated through its from inspiring English sources
The divergent role of PGE2 is amplified by the variety of different kinase-mediated signalling cascades that can be activated through its EP receptors, such as the protein kinase A (PKA), phosphatidylinositide 3-kinases (PI-3K), and protein kinase C (PKC) pathways [ 10].
Ataxia-telangiectasia mutated (ATM) is activated through its autophosphorylation at Ser-1981 Ser-1981 ATM-pS1981 ATM-pS1981
Finally, hTopBP1 is activated through its interaction with Ser 387-phosphorylated hRad9 [ 4].
LKB1 is activated through its ability to form a heterotrimeric complex with the pseudokinase STRAD (STE20-related kinase adaptor) and the scaffolding protein MO25 [ 5– 8].
These data suggested that once induced, Wip1 rapidly inactivates the JNK, p38 MAPK, and ATR pathways, thereby preventing a cytotoxic response after cellular exposure to IR. Upon treatment with apoptotic stimuli, proapoptotic BAX protein is activated through its phosphorylation by JNK, p38 MAPK, or GSK-3 β, resulting in its translocation to the outer mitochondrial membrane.
The Akt pathway can be activated through inactivation and downregulation of its negative regulator, PTEN [17].
As Elliott describes, much of this power is manifested through the physical realm and can be activated through intense physical activity.
Furthermore, MAPKs can also be activated through the upstream activation of HER2/neu or RAS.
The JAK/STAT3 pathway may be activated through interaction of the cytokine IL6 with its receptor.
Its protein product cannot be activated through tyrosine phosphorylation that is crucial for dimerization.
