Sentence examples for be activated through direct from inspiring English sources
A possible explanation for such regulation may be consistent with that PAK1 can be activated through direct interaction with PI3K [ 32] and can be indirectly activated by Akt [ 32].
Further work has now revealed that Tip60 is activated through direct interaction between Tip60's chromodomain and histone H3 trimethylated on lysine 9 (H3K9me3).
NLRs prevail in the cytoplasm in a dormant form and are activated through direct or indirect binding of ligands to the LRR-receptor domain.
Whether PI3Kγ is activated through direct or indirect interactions with the EpoR remains to be determined.
In this case, cell cycle is activated through direct amplification of cyclins and TP53 inactivating mutations unable cells to repress proliferation.
Nonetheless, presumably the inactivation of Gwl requires active/reactivated PP2A-B55, because Gwl is activated through direct phosphorylation by CDK1 (as previously reported by the authors).
Alternatively, JNK may be activated through other direct or indirect integrin signalling pathways.
In addition to direct AR binding, PI3K (and subsequently TOR) can be activated through receptor adaptor complexes such as those associated with Her2.
Lieblein, J. C. et al. STAT3 can be activated through paracrine signaling in breast epithelial cells.
For analysis of cellular interactions in vivo, direct observation of different types of cells being activated through the interactions is crucial.
