Sentence examples for be activated primarily by from inspiring English sources

DAAM1 can localize to the centrosome/Golgi region where Cdc42 has been reported to act [41], whereas plasma membrane Dvl2-DAAM1 may be activated primarily by RhoA.GTP.

PAK1 is activated primarily by binding to active Cdc42 or Rac1 [65], which in turn binds and activates MEK to stimulate ERK1/2 activation [66].

Although not directly compared in the present analysis, peak consumatory responses in the unpaired condition were significantly smaller than anticipatory peak responses in the paired condition (0.4 vs 0.2 μM), especially in the control offspring, again demonstrating that NAc DA transmission is activated primarily by conditioned cues that reliably predict a positive outcome.

ATR is activated by a wide spectrum of DNA damages inducing replication stress while ATM is activated primarily by DNA DSBs [ 9, 42, 43].

Isoforms of PLC-β are activated primarily by G protein-coupled receptors through members of the Gq/11 family of G proteins.

While during normal development STAT5 is activated primarily by PRL signaling pathways, EGF and GH signaling pathways can also contribute [ 32, 70].

Two nutrient-sensing pathways, namely Tor/S6K and Ras/PKA pathways, which are activated primarily by amino acids and glucose, respectively, have been identified as proaging pathways in Saccharomyces cerevisiae (budding yeast) and Schizosaccharomyces pombe [ 3, 4].

After interactions of cytokines, hormones, and growth factors with their respective cell surface receptors, STATs are activated, primarily by phosphorylation at tyrosine residues, and then dimerize and translocate to the nucleus.

This could lead to differences in membrane expansion and unfolding events, both of which may be associated with calcium signaling via SACs that are activated primarily by membrane tension (Sachs 2010).

Another example is the network of genes regulated by bZIP transcription factor OsTGA10 (Os06g41100) and R2R3-type Myb transcription factor OsMyb4 (Os04g43680), which is activated primarily in by oxidative signal stress during exposure to chilling and configures various components of oxidative defenses (Jakoby et al., 2002; Cheng et al., 2007; Park et al., 2010b; Yun et al., 2010; Xu et al., 2012).

CHK2 is activated primarily in response to DSB through the phosphorylation of T68 by ATM [ 25- 27] and subsequent oligomerization and autophosphorylation at T383 and T387 [ 28, 29].