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In order to be fully active, CPT-11 needs to be activated into the active compound SN-38 (7-ethyl-10-hydroxycamptothecin) by carboxylesterase (CE) enzymes (Tsuji et al, 1991; Satoh et al, 1994).
In an open surgical site, these products can be activated into a fibrin gel that offers additional local antihemorrhagic and sealing properties.
This work aims exploring the high performance porous separators that can be activated into gel electrolyte membranes for lithium ion batteries.
Once stimulated by certain mitogens, these cells would be activated into the cell cycle (by progressing from G0 into G1 and subsequently into S, G2, and M) and promoted to proliferate and differentiate.
Consequently, there is a reduction in the number of elements that are available to be activated into the A1 state, which results in a reduction in responding.
Capacity of macrophages to be activated into a pro-inflammatory state by chemokines and cytokines generally declines with aging (Sebastian et al., 2009).
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Upon activation of the coagulation cascade, prothrombin is activated into thrombin.
Once LCFA cross the membrane, most are activated into an LC-acyl-CoA (LCACoA) primarily via ACSL1 (activation shown by small red dots).
Wife said the battery commander called to say I had now been activated into the Federal Army and would have to report at 0645 hours tomorrow morning.
These whales were beached on the exact day U.S. Navy destroyers were activated into sonar exercise.
This brought about the planned command change, and at noon on 1 Aug 1944 Omar Bradley moved up to command the 12th Army Group, Courtney Hodges took over the First Army, and Patton's Third Army was activated into the group along with First Army, with Middleton's VIII Corps now falling under Patton.
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Justyna Jupowicz-Kozak
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