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These receptors, however, have similar functionality in neutrophils, suggesting that this same antiviral pathway might be activated in multiple cell types from the psoriatic epidermis [ 68].
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Our results are in accordance with a recent report [44] that the canonical Wnt signalling pathway is activated in multiple myeloma through constitutively active β-catenin.
A variety of signal pathways are activated in multiple cancer types.
First, these BLA neurons were activated in multiple animal models of anxiety (e.g., open field test, elevated plus maze test).
MAPKs, such as ERK, JNK, and p38MAPK, are activated in multiple drug resistance cells [ 38].
The PI3K/Akt pathway is activated in multiple cancers of different origin.
NF-κB is activated in Multiple Sclerosis also, for which EAE is an experimental animal model [ 28].
GCN4 is another transcription activator that is a master regulator of gene expression during amino acid starvation in S. cerevisiae and is activated in multiple stress responses [ 36].
Multiple oncogenes may be activated in a tumor, while multiple tumor-suppressor genes may be inactivated.
In addition, the proteins reported to be activated in normal cells and multiple cancer cell types are provided in Table 2. > -wrap-foot> > -wrap-foot> The pathway was manually represented using the visualization tool named 'PathVisio' (27).
It would be of particular interest to establish whether the RTK/RAS signalling pathway might be activated in GC due to multiple concomitant mutations of genes related to RTK/RAS signalling or concomitant gene amplifications also present in only small subsets of GC (Deng et al, 2012).
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