In addressing the role of complement in tissue injury, two central questions arise: how complement is activated in each type of injury, and to what extent is complement activation responsible for tissue injury?
In CA3, distinct subsets of pyramidal cells were activated in each room, regardless of the similarity of the testing enclosure.
Given these differences in genes that are activated in each ligands group that are categorized based on the sub-regions on the cAMP-Calcium space, a next natural question to ask is what transcriptional factors are involved in the expression of genes in different sub-regions and how specific are they?
This suggests that these metabolic or signal pathways are activated in each tissue.
Different signaling cascades are activated in each stage (before and after anastomosis).
This would give an indication of whether or not the same representational space is being activated in each case.
Using normal mesothelial cells (97 510 and HM3) as a reference point, AKT and S6 were activated strongly in each of five mesothelioma cell lines (MESO924, MESO257, MESO296, MESO428, and JMN1B) and MAPK (MAPK1/3) was activated in each line except JMN1B.
Different treatments may promote either active or spontaneous release (for example, Nosyreva & Kavalali, 2010; Sara et al, 2011), although it is unclear whether this indicates that a different pool of vesicles is activated in each case.
Our analysis of the activation status of KIT in 17 KIT-positive GISTs by the detection of phosphorylated tyrosine residues shows that at least a fraction of KIT was activated in each tumour, even in the absence of gain-of-function mutation, consistent with previously published data (Rubin et al, 2001; Heinrich et al, 2003b; Antonescu et al, 2005).
All three origins are activated in each round of replication within a narrow temporal window (Duggin et al, 2008a), and marker frequency analyses (MFAs) have revealed that replication forks meet approximately mid-way between the origins whereupon replication fork fusion (termination) occurs (Lundgren et al, 2004; Duggin et al, 2008a).
