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Our data show that quiescent NK cells can be activated by direct cell contact with dendritic cells (CD).
Interestingly, Tiam1 can also be activated by direct interaction with the neurotrophin effector H-Ras [19].
However, PKDs can also be activated by direct binding of diacylglycerol (DAG) to the C1a domain within their regulatory domain [17].
Slpr can be activated by direct interaction with either Msn or the Rac1 GTPase.
This suggests that, in addition to intronic snoRNAs (our data), independently transcribed snoRNAs might be activated by direct Myc binding.
Src could also be activated by direct binding of its SH2 and SH3 domains to intracellular proteins or activated tyrosine kinase growth factor receptors [ 58].
Similar(51)
First, Bach1 possesses an exportin1/Crm1-dependent nuclear export signal (NES) whose activity is activated by direct heme binding (Fig. 1A).
PLCγ is activated by direct SH2-domain-dependent interaction with activated tyrosine kinase receptors and subsequent phosphorylation [ 32, 33].
The data are very strong that Bax is activated by direct interaction with BH3-only proteins.
The alternative pathway is activated by direct binding of hydrolyzed C3b to the surface of bacterial membranes.
CgPdr1 is activated by direct binding of various compounds, including azoles that are antifungal drugs (Thakur et al. 2008).
More suggestions(15)
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