Sentence examples for be activated by binding from inspiring English sources

To become functional, PPARγ must be activated by binding an appropriate ligand.

In the previous example it was electrical bias, but other channels can be activated by binding a molecular agonist or through a conformational change in another nearby protein.

We chose EphA4 because it can be activated by binding either ephrin-As or ephrin-Bs [11], is found at synapses in mature brain [13], and regulates dendritic spine morphology in hippocampus [28].

DOI: http://dx.doi.org/10.7554/eLife.00378.017 LIN-12 is a membrane-associated protein that can be activated by binding with its ligand.

To analyze whether SMED-SL disease mutants could be activated by binding to collagen, we transiently expressed the mutants and wild-type DDR2 in HEK293 cells.

Later in life, these previously quiescent QKRAA-specific T cells can be activated by binding with high avidity an exogenous peptide containing the SE [ 101].

As mentioned before, SRC is activated upon binding to activated ERBB2, whereas PI3K is activated by binding to activated ERBB3.

Retinoic acid receptors (RARs) are transcriptional activators which are activated by binding of their ligands and act in concert with a combination retinoid X type receptors (RXR alpha, beta and gamma).

ROK-α is a direct effector of the Rho GTPase, which is activated by binding to active Rho [ 63].

RAF is activated by binding with the active form of RAS, which subsequently stimulates the mitogen-activated protein kinase extracellular-signal-regulated kinase extracellular-signal-regulated a cascade of autophosphorylation events towards cell proliferation (Fig.  1) [ 30].

EC 2.7.11.1) is activated by binding of Rho-GTP (active) to its Rho-binding domain, which induces a conformational change in the enzyme exposing its kinase domain and rendering it active (Ridley, 2001; Schofield & Bernard, 2013; Somlyo & Somlyo, 2000).