Sentence examples for be activated and expanded from inspiring English sources

The ovalbumin-specific CD8+ Tc cells were found to be activated and expanded in the renal lymph nodes, and the activation of T cells in turn could be prevented by depletion of DCs.

There was something anticlimactic about yesterday's launch of an American and two Russians toward the International Space Station, whose first linked modules are now circling 240 miles overhead, ready to be activated and expanded.

Moreover, when encountering antigens, the infused CAR T cells can be activated and expanded by over one hundred- to thousand-fold to cause more severe toxicities, such as what has already been reported for the high-affinity HER2/neu (ErbB2) CAR derived from the humanized monoclonal antibody trastuzumab to treat a colon cancer patient (Morgan et al., 2010).

Based on these postulates, a potential treatment approach would be to isolate Tregs from donor blood prior to the transplantation, which would then be activated and expanded with allogeneic DCs from the host recipient.

V γ9V δ2 T cells have a unique capacity to recognise and be activated and expanded by non-peptide phosphoantigens, including aminobisphosphonate drugs, such as zoledronate and pamidronate.

Thus, it is desirable to incorporate many tumour antigens into a DC-based vaccine, so CTL that recognise diverse tumour epitopes can be activated and expanded to prevent tumour escape.

Plasmacytoid DCs and CD8+ DCs were activated and expanded in the presence of plasmid encoding Flt3L.

In adoptive cell therapy (ACT), autologous tumor-specific T-cells isolated from cancer patients are activated and expanded ex vivo, then infused back into the individual to eliminate metastatic tumors.

Exposure to exogenous RA inhibits genes normally expressed in the most anterior endoderm, while genes transcribed at the level of branchial arches are activated and expanded anteriorly.

Using lymphocytic choriomeningitis virus (LCMV) peptide gp33-specific CD8+ T cells derived from T cell receptor transgenic mice, we characterized the metabolic phenotype of proliferating T cells that were activated and expanded in vitro in the presence or absence of rapamycin, and determined the capability of these rapamycin-treated T cells to generate long-lived memory cells in vivo.

The PBMCs or V γ9V δ2 T cells were activated and expanded with pamidronate (PAM) and interleukin-2 (IL-2) with or without the presence UC-MSCs.