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12 Thus, monoclonal antibodies that bind CTLA-4 were developed as anticancer therapies under the theory that through blockade of the CTLA-4-mediated inhibitory signal, the activity of T-cells may be activated against tumor antigens and their activity harnessed for treatment of cancer.
If the immune organs could be activated against a cancer, we might find a pathway through the jungle and, maybe, to a cure.
Taken together, these data suggest that systemic melanoma-specific mature B cell responses may be present in patients with melanoma and may harbor the potential to be activated against cancer cells.
Since the patient developed only ileitis without colitis - as reported in the most of patient in the phase III study - we can suppose that two different autoimmune pathways could be activated against colic and ileal epitopes.
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Nearly 1,300 unique companies were activated against from 2010 to 2015.
Some GMO crops do not involve an added protein such as GMO papaya in Hawaii, the immune system of which is activated against the papaya ringspot virus.
Once the immune system is activated against the poliovirus-infected tumor, the cancer cells can no longer hide and they remain vulnerable to ongoing immune attack.
Since donor alloreactive T-cells are also being activated against host epitopes presented on normal tissues, graft-versus-host disease (GVHD) [29], [30] is the most common threatening complication post allogeneic transplantation.
Following application of the plasters, the applicator was activated against each plaster to ensure consistent MN penetration in each volunteer (confirmed using OCT, as described previously).
Positive TLR2 expression in the microenvironment suggests that immune surveillance is activated against the altered cells, whereas TLR2 expression by malignant keratinocytes may correlate with apoptosis resistance and, hence, the survival of tumour cells.
Moreover, it might be a unique characteristic of CMV infections that CD8+ T-cells are activated against highly promiscuous epitopes presented by MHC class II molecules, as demonstrated in rhesus cytomegalovirus infection [ 165].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com