Sentence examples for be achieved through activation from inspiring English sources

This may be achieved through activation or inhibition of intracellular signaling pathways, which have been implicated in the regulation of mitochondrial ROS production but also other proteins can be of interest for therapeutic intervention.

44 This suggests that also nigral D1 receptors contribute to LID, and that the l-DOPA induced increase of nigral GABA release might be achieved through activation of both striatal postsynaptic D1 receptors located on dMSNs and nigral D1 receptors located on striato-nigral GABA afferents.

In about 90% of cancers, this is achieved through activation and upregulation of the telomerase pathway (Shay and Wright, 1996; Verdun and Karlseder, 2007; O'Sullivan and Karlseder, 2010).

This was achieved through activation of AKT/ERK1/2-mediated phosphorylation of I κB- α and NF- κB and not stimulation of the JNK pathway [ 165].

Increased defense against a variety of pathogens in plants is achieved through activation of a mechanism known as systemic acquired resistance (SAR).

Thus the extent of translational up-regulation attained through the concerted activation of mTOR by multiple pathways in 293T could be achieved through its activation primarily by the PA pathway in PC3.

This would be achieved through the activation of a rapid response team lead by an intensivist acting in accordance with an intervention flowchart.

When the same receptor is employed to trigger distinct biological responses in a given cell type, each response can be achieved through the activation of distinct signalling cascades.

Elevation of intracellular cAMP levels can be achieved through the activation of adenylate cyclase either directly or through appropriately coupled membrane receptors, as well as by preventing the hydrolysis of cAMP by the cyclic nucleotide phosphodiesterases.

The non-canonical ECM-dependent pathway downstream of PI3K described here provides an explanation for the diversity of cellular responses that can be achieved through the activation of pAkt1.

Here, we show that similar reprogramming can also be achieved through the direct activation of endogenous genes using engineered CRISPR/Cas9-based transcriptional activators.